Frontotemporal lobar degeneration is the fourth cause of dementia in people over 65 years old. New discoveries found genetic variants in TMEM106B as an strong risk factor for developing this neuropathology.
La degeneración lobular frontotemporal es la cuarta causa de demencia en gente mayor de 65 años . Nuevos descubrimientos describen la presencia de variantes genéticas de TMEM106B como importante factor de riesgo para desarrollar esta neuropatología.
Van Deerlin, V. M., Sleiman, P. M. A., Martinez-Lage, et al. (2010). Common variants at 7p21 are associated with frontotemporal lobar degeneration with tdp-43 inclusions. Nature Genetics , advance online publication. URL http://dx.doi.org/10.1038/ng.536
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